deleterious mutations

deleterious mutations
Мутации вредные — мутации, снижающие выживаемость их носителей обычно в пределах от 10 до 100%. К этой группе относится большинство спонтанных и индуцированных мутаций, вызывающих видимые изменения (см. Мутации видимые. Мутации жизнеспособности). По оценкам М. Кимуры, около 90% мутаций являются вредными и около 10% — селективно нейтральными или полезными. Кроме того, мутация, вредная в большой популяции, может оказаться селективно нейтральной в малой популяции, что в свою очередь приводит к увеличению скорости изменений на молекулярном уровне.

Англо-русский толковый словарь генетических терминов. — М.: Изд-во ВНИРО. . 1995.

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